David E. Elder, MBChB

Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
Professor of Dermatology
Perelman School of Medicine at the University of Pennsylvania 

Director, Dermatopathology Service
Hospital of the University of Pennsylvania

Contact InformationHospital of the University of Pennsylvania
Division of Anatomic Pathology, 6 Founders
3400 Spruce Street
Philadelphia, PA 19104

Office: 215-662-6503
Fax: 215-349-8088


Specialty Division

Anatomic Pathology

Research Expertise

Studies in diagnosis, prognosis, genetics and therapy of melanoma.

Clinical Expertise

Dermatopathology, with special interest in pathology of melanoma and pigmented lesions.


BMedSc University of Otago School of Medicine, Dunedin, New Zealand , 1969
MBChB University of Otago School of Medicine, Dunedin, New Zealand , 1970
Diplomate (Clinical Pathology), University of Otago School of Medicine, Dunedin, New Zealand , 1975

Specialty Certification

Diploma in Clinical Pathology, University of Otago School of Medicine, Dunedin, New Zealand, 1974
Fellow, Royal College of Pathologists of Australia (now Australasia) (by examination in anatomic pathology), 1976

Postgraduate Training

Rotating Intern, Rotorua Public Hospital, Rotorua, New Zealand, 1971-1972
Pathology Registrar (resident), Dunedin Public Hospital, Dunedin, New Zealand, 1972-1975

Awards and Honors

National Junior Scholarship, New Zealand Department of Education, 1963-1966
Batchelor Memorial Medal and Prize for Obstetrics & Gynecology, University of Otago School of Medicine, 1970
ICRETT traveling award, WHO International Union against Cancer, 1982
Peter C Nowell Teaching Award, University of Pennsylvania, 1989
American Skin Association. Skin Cancer Research Award, 1998
Distinguished Fellow (Citation and Gold Medal), Royal College of Pathologists of Australasia, 2004
American Association for the Advancement of Science - elected Fellow, 2005
The Dr Neil Smith Medal for Outstanding Contributions to Dermatopathology, presented by the British Society for Dermatopathology., 2011
Honorary Life Membership, British Society of Dermatopathology, 2011

Memberships and Professional Organizations

New Zealand Medical Association, 1976 - 1985
Royal College of Pathologists of Australia, 1977 - Present
American Association for the Advancement of Science, 1978 - Present
US-Canadian Academy of Pathology, 1978 - Present
Arthur Purdy Stout Society of Surgical Pathologists, 1978 - 2005
International Academy of Pathology, 1978 - 2005
Australian Society of Dermatopathology, 1980 - 1985
International Society of Dermatopathology, 1985 - Present
John Morgan Society, 1985 - Present
American Society for Cancer Research, 2000 - 2005
International Pigment Cell Society, 2000 - 2005
American Society of Human Genetics, 2004 - 2008
American Society of Investigative Pathology, 2005 - 2010
International Melanoma Pathology Study Group, 2008 - Present
British Society for Dermatopathology, 2011 - Present
Pathology Society of Philadelphia, 2013 - Present
Society for Melanoma Research, 2014 - Present

Web Links

Selected Publications

Lever's Histopathology of the Skin. Ninth Edition.

Elder, DE, Editor-in-Chief, R Elenitsas, BL Johnson Jr, GF Murphy, Lippincott Williams & Wilkins, Philadelphia. ISBN 0-7817-3742-7, 2005

Mitotic rate as a predictor of sentinel lymph node positivity in patients with thin melanomas.

Kesmodel SB, Giorgos C, Karakousis GC, Botbyl JD, Canter RJ, Lewis RT, Wahl PM, Alavi A, Elder DE, Ming ME, Guerry D, Gimotty PA, Fraker DL, Czerniecki BJ, Spitz FR, Ann Surg Oncol 12(6): 449-458, 2005, PMID:15864482

Read article

A tumorigenic subpopulation with stem cell properties in melanomas

Fang D, Nguyen TK, Leishear K, Finko R, Kulp AN, Hotz S, Van Belle PA, Xu X, Elder DE, and Herlyn M, Cancer Research submitted, 2005, PMID:16230395

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Preferential involvement of CX-chemokine receptor-4 and CX-chemokine ligand-12 in T-cell migration toward melanoma cells

Zhang T, Somasundaram R, Caputo L, Van Bell P, Elder D, Czerniecki B, Hotz S, Schuchter L, Fraker D, Spitz FR, Berensci K, Rani P, Marincola F, Qui R, and Herlyn D, Submitted JNCI, 2005

Wistar Institute/University of Pennsylvana Skin Cancer SPORE Phase II trials of sorafenib (BAY 43-9006) in melanoma: efficacy in combination with chemotherapy and correlative studies of mechanism of action in metastatic melanoma. Annual SPORE meeting, Bethesda, MD

Flaherty KT, Schuchter LM, Tuveson D, Elder D, Van Belle P, Johnson S, Rosen M, Redlinger M, Weber B, O'Dwyer PJ, SPORE Annual Meeting Abstracts, 2005