PEOPLE

Priti Lal, MD

Associate Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
University of Pennsylvania Perelman School of Medicine

Contact InformationDepartment of Pathology and Laboratory Medicine
Hospital of the University of Pennsylvania
6 Founders Pavilion
3400 Spruce Street
Philadelphia, PA 19104-4283
Office: 215-662-6505

Email: priti.lal@pennmedicine.upenn.edu

Specialty Division

Anatomic Pathology

Research Expertise

Application of high through-put technology to gain insights into the biology of human cancers, with special interest in GU cancers.

Clinical Expertise

GU Pathology

Education

B.S. (Genetics), Delhi University, Delhi, India, 1984
MD Maulana Azad Medical College, Delhi, India, 1990

Specialty Certification

American Board of Pathology, Anatomic Pathology, 2010
American Board of Pathology, Anatomic Pathology (Recertification), 2020

Postgraduate Training

Fellow, Molecular Biology, National Institutes of Health, Bethesda, MD, 1993-1995
Fogarty Fellow, National Institutes of Health, Bethesda, MD, 1993-1995
Resident, Pathology, UMDNJ-New Jersey Medical School, Newark NJ, 1996-2000
Visiting Fellow, GI and Liver Pathology, Armed Forces Institute of Pathology, Washington, DC, 1999-1999
Fellow, Oncologic Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, 2000-2001
Fellow, Diagnostic Molecular Pathology, Memorial Sloan Kettering Cancer Center, New York, NY, 2001-2002
Fellow, Research, Memorial Sloan Kettering Cancer Center, New York, NY, 2002-2004

Awards and Honors

Fogarty International Fellowship, NIA, NIH, 1993-1995
Lucien J. Rubinstein Award" for the best Neuropath-oncology paper at the 2010 AANP meeting in Philadelphia, 2010
Nominated for Young investigator award at Cardiovascular society, USCAP 2012.
Platform Presentation. Senior author paper.
Mentored Resident, 2012
Awarded "Poster of Distinction" American Transplant Congress. Senior Author paper. Mentored Resident, 2012
Nominated for the Training and Education commitee for Solid tumors. Association for Molecular Pathologists, 2012
Nominated for Kevin E. Salhany award and the James Wheeler Award, for excellence in clinical teaching and education, 2012
Nominated for Preclinical Teaching Award, Perelman School of Medicine by class of 2017, 2014
Leading Success, University of Pennsylvania, 2017-2018
GU Oncologic disease, FY19 Innovation contest winner
Muscle invasive bladder cancer precision panel (MiBCa Panel) for treatment and prognosis: A Penn multidisciplinary initiative towards personalized treatment of bladder cancer, 2018
Scholar,Center for Global Health, Perelman School of Medicine, 2020

Memberships and Professional Organizations

Pennsylvania Association of Pathologists, 2008 - Present
Association for Molecular Pathology, 2010 - 2011
American Society for Clinical Pathology, 2010 - 2011
United States and Canadian Academy of Pathologists, 2010 - 2011
College of American Pathologists, 2010 - Present
ISUP, 2015 - Present
AACR, 2015 - Present
ASCO, 2018 - Present

Web Links


Selected Publications

Tumor Hypoxia Recruits Regulatory T Cells via the CCL28 Chemokine to Promote Immune Tolerance and Angiogenesis

Andrea Facciabene, Xiaohui Peng, Ian S. Hageman, Andrea Barchetti, Klara Balint, Li-Ping Wang, C. Blake Gilks, Priti Lal, Lin Zhang, George Coukos, Nature. 2011 Jul 13;475(7355):226-30. doi: 10.1038/nature10169., 2011, PMID:21753853

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Novel Biomarker Signature That May Predict Aggressive Disease in African American Men With Prostate Cancer.

Yamoah K, Johnson MH, Choeurng V, Faisal FA, Yousefi K, Haddad Z, Ross AE, Alshalafa M, Den R, Lal P, Feldman M, Dicker AP, Klein EA, Davicioni E, Rebbeck TR, Schaeffer EM., J Clin Oncol. 2015 Sep 1;33(25):2789-96. doi: 10.1200/JCO.2014.59.8912. Epub 2015 Jul 20., 2015, PMID:26195723

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Phase 2 trial of the cyclin-dependent kinase 4/6 inhibitor palbociclib in patients with retinoblastoma protein-expressing germ cell tumors.

Vaughn DJ, Hwang WT, Lal P, Rosen MA, Gallagher M, O'Dwyer PJ., Cancer. 2015 May 1;121(9):1463-8. doi: 10.1002/cncr.29213. Epub 2014 Dec 18., 2015, PMID:25522918

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COX-2 mediates pro-tumorigenic effects of PKCε in prostate cancer

Rachana Garg, Jorge M Blando, Carlos J Perez, Priti Lal, Michael D Feldman, Emer M Smyth, Emanuela Ricciotti, Tilo Grosser, Fernando Benavides, Marcelo G Kazanietz, Oncogene. 2018 Aug;37(34):4735-4749. doi: 10.1038/s41388-018-0318-9. Epub 2018 May 16. 37(34): , 2018, PMID:29765153

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Digital features of stromal morphology in prostate cancer differ between African-Americans and Caucasians and are prognostic of recurrence following prostatectomy

Hersh Bhargava, Patrick Leo, Robin Elliott, Andrew Janowczyk, Jon Whitney, Sanjay Gupta, Pingfu Fu, Kosj Yamoah, Timothy Rebbeck, Michael Feldman, Priti Lal, and Anant Madabhushi, Clinical cancer Research, 2018

CDK7 inhibition suppresses Castration- Resistant Prostate Cancer through MED1 inactivaion

Rasool RU, Natesan R, Deng Q, Aras S, Lal P, Sander Effron S, Mitchell-Velasquez E, Posimo JM, Carskadon S, Baca SC, Pomerantz MM, Siddiqui J5, Schwartz LE, Lee DJ, Palanisamy N, Narla G, Den RB, Freedman ML, Brady DC, Asangani IA, Cancer Discov. 2019 Nov;9(11):1538-1555., 2019, PMID:31466944

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PDL-1 Expression reveals significant association with squamous differentiation in Upper Tract Urothelial Carcinoma

Aileen Grace P. Arriola, Sahar J. Farahani, Hersh K. Bhargava, Thomas J. Guzzo, John S.J. Brooks and Priti Lal, Am J Clin Pathol. 2019 May 3;151(6):561-573., 2019, PMID:30776071

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Differences in PD-L1 Expressing Macrophages and Immune Micro-environment in Testicular Germ Cell Tumors

Sam Sadig, Sahar Farhani, Abhishekh Shah, David Vaughn, Priti Lal, Am J Clin Pathol. 2020 Feb 8;153(3):387-395 153(3): 387-395, 2020, PMID:31802108

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A Phase 1 Clinical Trial of PSMA-directed/TGFβ-insensitive CAR-T cells in Metastatic Castration-Resistant Prostate Cancer

Vivek Narayan, Naomi Haas, Priti Lal et al, ASCO 2020, 2020

Computationally derived image signature of stromal morphology is prognostic of prostate cancer recurrence following prostatectomy in African American patients

Hersh K. Bhargava, Patrick Leo, Robin Elliott, Andrew Janowczyk, Jon Whitney, Sanjay Gupta4, Pingfu Fu, Kosj Yamoah, Francesca Khani, Brian D. Robinson, Timothy R. Rebbeck, Michael D. Feldman1, Priti Lal, Anant Madabhushi, Clin Cancer Res. 2020 Apr 15;26(8):1915-1923. 26(8): 1915, 2020, PMID:32139401

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