Matthew B. Palmer, MD, PhD
Associate Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
Perelman School of Medicine at the University of Pennsylvania
Director, Renal Pathology Service
Hospital of the University of Pennsylvania
Contact InformationHospital of the University of Pennsylvania
6 Founders Pavilion
3400 Spruce Street
Philadelphia, PA 19104
Email: matthew.palmer@pennmedicine.upenn.edu
Specialty Division
Anatomic Pathology
Education
BS (Zoology and Russian), Brigham Young University, 1998
MD (Doctor of Medicine), Emory University School of Medicine, 2008
PhD (Biochemistry, Cell, and Developmental Biology), Emory University, 2008
Specialty Certification
American Board of Pathology, Anatomic and Clinical Pathology, 2012
Postgraduate Training
Resident, Anatomic and Clinical Pathology, Yale-New Haven Hospital/Yale School of Medicine, 2008-2012
Fellow in Renal and Genitourinary Pathology, Department of Pathology, Yale School of Medicine, New Haven, CT, 2012-2013
Awards and Honors
University Scholarship, Brigham Young University, 1992
DOE Undergraduate Research Fellowship, UC Davis, 1996
Dean's List, College of Biology and Agriculture, Brigham Young University, 1996
NSF Research Training Program, National Museum of Natural History, 1998
NIH Medical Scientist Training Program Fellowship, Emory University, 1999-2008
NIH Cell and Molecular Biology Training Grant, Emory University, 2005
Woodruff Scholarship, Emory University School of Medicine, 2007-2008
Memberships and Professional Organizations
Renal Pathology Society, 2012-present
United States and Canadian Academy of Pathology, 2012-2014
College of American Pathologists, 2012-2014
Nephrotic Syndrome Study Network (NEPTUNE), 2013-present
American Society of Nephrology, 2015-present
Cure Glomerulonephropathy Network (CureGN), 2016-present
Transformative Research in Diabetic Nephropathy (TRIDENT), 2016-present
Web Links
Selected Publications
Percutaneous Native Kidney Biopsy Complications in Diabetic Patients in the TRIDENT Cohort
Mohandes S, Fakhreddine M, Sheng H, Al Dulaimee M, Mottl A, Scialla J, Almaani S, Luciano R, Isakova T, Bansal S, Argyropoulos C, Avasare R, Singh M, Campbell KN, Townsend R, Coppock G, Palmer M, Susztak K; TRIDENT Consortium., Clinical Journal of the American Society of Nephrology, 2026, PMID:42295857
Kidney Transplantation in Two Highly Sensitized Candidates after CAR T-Cell Therapy.
Bhoj VG, Kaminski M, Zhao H, Jackson K, Wang W, Liu C, Montgomery RA, Ali N, Mangiola M, Spitzer TR, Safa K, Pattanayak V, Taj R, Chiu J, Bui TM, Sonnenberg EM, Markmann JF, Milone MC, June CH, Siegel DL, Fraietta JA, Gonzalez V, Locci M, Palmer M, Monos D, Hwang WT, Sledge T, Bridges ND, Goldstein JS, Odim J, Sweet SC, Besharatian BD, Hussain SM, Brown NK, Kamoun M, Garfall AL, Naji A., New England Journal of Medicine 394(21): 2117-2125, 2026, PMID:42235014
Spatial atlas of diabetic kidney disease reveals a B cell-rich subgroup.
Dumoulin B, Levinsohn J, Klötzer KA, Li C, Mao L, Ha E, Mohandes S, Nguyen T, Paruzzo L, Hirohama D, Fang V, Bhoj VG, Parhiz H, Andrade-Silva M, Abedini A, Bergeson A, Traum D, May MJ, Kaestner KH, Ruella M, McAllister FE, Hakimi AA, Li M, Palmer M, Wherry EJ, Hunter CA, Cancro MP; TRIDENT consortium; Susztak K., Nature 653(8116): 1158-1169, 2026, PMID:42056516
Treatment of atypical hemolytic uremic syndrome and C3 glomerulopathy in mice by hepatic expression of factor D
Kim H, Golla M, Gullipalli D, Halle W, Miwa T, Palmer M, Song WC., Blood Advances 10(6): 2024-2037, 2026, PMID:41544220
Chimeric antigen receptor T cells against the IGHV4-34 B cell receptor specifically eliminate neoplastic and autoimmune B cells.
Cohen IJ, Bochi-Layec AC, Lemoine J, Jenks S, Bayat P, Kim KH, Zhao H, Ugwuanyi O, Stella F, Ghilardi G, Gabrielli G, McCuaig S, Iatrou A, Vlachonikola E, Karipidou M, Bouziani E, Espie D, Ramasubramanian R, Agathangelidis A, Bhosale A, Paruzzo L, Medico G, Kolar B, Bugrovsky R, Guruprasad P, Wang LP, Harris J, Arons E, Zhang Y, Pajarillo R, Kreiger PA, Day CP, Sahinalp SC, Wu CH, Santi A, Fulmer B, Cases M, Palmer MB, Porazzi P, Wherry EJ, Kreitman RJ, Tiacci E, Apostolidis SA, Behrens EM, Bhoj V, Sanz I, Inghirami G, Schuster SJ, Ghia P, Stamatopoulos K, Ruella M., Science Translational Medicine 18(835): , 2026, PMID:41637528
Unbiased self supervised learning of kidney histology reveals phenotypic and prognostic insights
Pandit K, Coudray N, Quiros AC, Surapaneni A, Upadhyay D, Vanguri RS, Hirohama D, Mohandes S, Schlosser P, Thiessen-Philbrook H, Wen Y, Parikh CR, Rhee EP, Waikar SS, Schmidt I, Rosenberg AZ, Palmer MB, Susztak K, Grams ME, Tsirigos A; TRIDENT Study Investigators, Scientific Reports 15(1): 35131, 2025, PMID:41062686
The actin and microtubule network regulator WHAMM is identified as a key kidney disease risk gene.
Dhanunjay Mukhi, Lakshmi Prasanna Kolligundla, Tomohito Doke, Magaiver Andrade- Silva, Hongbo Liu, Matthew Palmer, Katalin Susztak, Cell Reports 44(4): , 2025, PMID:40138314
Zebra Bodies in Kidney Biopsy: Drug-Induced Phospholipidosis in a Patient With Systemic Lupus Erythematosus.
Aguila T, Madan R, Palmer MB, Derk CT, Journal of Rheumatology, 2025, PMID:40041993
Kidney multiome-based genetic scorecard reveals convergent coding and regulatory variants.
Liu H, Abedini A, Ha E, Ma Z, Sheng X, Dumoulin B, Qiu C, Aranyi T, Li S, Dittrich N, Chen HC, Tao R, Tarng DC, Hsieh FJ, Chen SA, Yang SF, Lee MY, Kwok PY, Wu JY, Chen CH, Khan A, Limdi NA, Wei WQ, Walunas TL, Karlson EW, Kenny EE, Luo Y, Kottyan L, Connolly JJ, Jarvik GP, Weng C, Shang N, Cole JB, Mercader JM, Mandla R, Majarian TD, Florez JC, Haas ME, Lotta LA; Regeneron Genetics Center‡; GHS-RGC DiscovEHR Collaboration§; Drivas TG; Penn Medicine BioBank¶; Vy HMT, Nadkarni GN, Wiley LK, Wilson MP, Gignoux CR, Rasheed H, Thomas LF, Åsvold BO, Brumpton BM, Hallan SI, Hveem K, Zheng J, Hellwege JN, Zawistowski M, Zöllner S, Franceschini N, Hu H, Zhou J, Kiryluk K, Ritchie MD, Palmer M, Edwards TL, Voight BF, Hung AM, Susztak K, Science 387(6734): 4753, 2025, PMID:39913582
Improved therapeutic efficacy of a bifunctional anti-C5 mAb-FH SCR1-5 fusion protein over anti-C5 mAb in an accelerated mouse model of C3 glomerulopathy.
Sato S, Miwa T, Gullipalli D, Golla M, Mohammadyari E, Zhou L, Palmer M, Song WC., Immunohorizons 9(3): , 2025, PMID:39865974
