Matthew B. Palmer, MD, PhD

Assistant Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
University of Pennsylvania Perelman School of Medicine

Contact InformationHospital of the University of Pennsylvania
6 Founders
3400 Spruce Street
Philadelphia, PA 19104


Specialty Division

Anatomic Pathology


B.S. (Zoology and Russian), Brigham Young University, 1998
M.D. (Doctor of Medicine), Emory University School of Medicine, 2008
Ph.D. (Biochemistry, Cell, and Developmental Biology), Emory University, 2008

Specialty Certification

American Board of Pathology, Anatomic and Clinical Pathology, 2012

Postgraduate Training

Resident, Anatomic and Clinical Pathology, Yale-New Haven Hospital/Yale School of Medicine, 2008-2012
Fellow in Renal and Genitourinary Pathology, Department of Pathology, Yale School of Medicine, New Haven, CT, 2012-2013

Awards and Honors

University Scholarship, Brigham Young University, 1992
DOE Undergraduate Research Fellowship, UC Davis, 1996
Dean's List, College of Biology and Agriculture, Brigham Young University, 1996
NSF Research Training Program, National Museum of Natural History, 1998
NIH Medical Scientist Training Program Fellowship, Emory University, 1999-2008
NIH Cell and Molecular Biology Training Grant, Emory University, 2005
Woodruff Scholarship, Emory University School of Medicine, 2007-2008

Memberships and Professional Organizations

Renal Pathology Society, 2012 - present
United States and Canadian Academy of Pathology, 2012 - 2014
College of American Pathologists, 2012 - 2014
American Society of Nephrology, 2015 - present

Web Links

Selected Publications

Epigenomic and transcriptomic analyses define core cell types, genes and targetable mechanisms for kidney disease

Liu H, Doke T, Guo D, Sheng X, Ma Z, Park J, Vy HMT, Nadkarni GN, Abedini A, Miao Z, Palmer M, Voight BF, Li H, Brown CD, Ritchie MD, Shu Y, Susztak K., Nature Genetics 54(7): 950-962, 2022, PMID:35710981

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Antisense oligonucleotides ameliorate kidney dysfunction in podocyte-specific APOL1 risk variant mice

Yang YW, Poudel B, Frederick J, Dhillon P, Shrestha R, Ma Z, Wu J, Okamoto K, Kopp JB, Booten SL, Gattis D, Watt AT, Palmer M, Aghajan M, Susztak K., Molecular Therapeutics 30(7): 2491-2504, 2022, PMID:35450819

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Quantification of Glomerular Structural Lesions: Associations With Clinical Outcomes and Transcriptomic Profiles in Nephrotic Syndrome.

Hodgin JB, Mariani LH, Zee J, Liu Q, Smith AR, Eddy S, Hartman J, Hamidi H, Gaut JP, Palmer MB, Nast CC, Chang A, Hewitt S, Gillespie BW, Kretzler M, Holzman LB, Barisoni L, American Journal of Kidney Diseases 79(6): 807-819, 2022, PMID:34864148

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Renal oncocytoma with both lymphovascular invasion and prominent intracytoplasmic vacuole-like spaces: a case report and review of the literature

Luo X, Preciado C, Nayak A, Schwartz LE, Guzzo T, Williamson SR, Palmer MB, Lal P, International Journal of Surgical Pathology 30(3): 300-306, 2022, PMID:34488464

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End Stage Mitochondrial Cardiomyopathy and Heart Transplantation Due to Biallelic Pathogenic C1QBP Variants

Wilcox NS, Prenner SB, Cevasco M, Condit C, Goldstein A, Peterson JT, Tondi Resta I, Palmer M, Lal P, Owens AT, Pieretti J, Drivas TG, Reza N., Circulation Genomics and Precision Medicine 15(2): , 2022, PMID:35119291

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Single-cell analysis highlights differences in druggable pathways underlying adaptive or fibrotic kidney regeneration

Balzer MS, Doke T, Yang YW, Aldridge DL, Hu H, Mai H, Mukhi D, Ma Z, Shrestha R, Palmer MB, Hunter CA, Susztak K, Nature Communications 13(1): 4018, 2022, PMID:35821371

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Genome-wide association studies identify the role of caspase-9 in kidney disease

Doke T, Huang S, Qiu C, Sheng X, Seasock M, Liu H, Ma Z, Palmer M, Susztak K., Science Advances 7(45): , 2021, PMID:34739325

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APOL1 risk variants in individuals of African genetic ancestry drive endothelial cell defects that exacerbate sepsis

Wu J, Ma Z, Raman A, Beckerman P, Dhillon P, Mukhi D, Palmer M, Chen HC, Cohen CR, Dunn T, Reilly J, Meyer N, Shashaty M, Arany Z, Haskó G, Laudanski K, Hung A, Susztak K., Immunity 54(11): , 2021, PMID:34715018

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The key role of NLRP3 and STING in APOL1-associated podocytopathy

Wu J, Raman A, Coffey NJ, Sheng X, Wahba J, Seasock MJ, Ma Z, Beckerman P, Laczkó D, Palmer MB, Kopp JB, Kuo JJ, Pullen SS, Boustany-Kari CM, Linkermann A, Susztak K, Journal of Clinical Investigation 131(20): , 2021, PMID:34651582

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New onset proteinuria in a patient with schwannoma

Abu Salman L, Kallis C, Palmer M, Bahrainwala J, Geara AS, American Journal of Kidney Disease 78(3): A12-A15, 2021, PMID:34420678

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