PEOPLE

Vinodh Pillai, MD, PhD

Assistant Professor of Pathology and Laboratory Medicine at the Children's Hospital of Philadelphia
University of Pennsylvania Perelman School of Medicine

Contact InformationThe Children's Hospital of Philadelphia
Department of Pathology and Laboratory Medicine
Philadelphia, PA, 19104
Fax: 215-590-1736

Research Expertise

CAR T cell therapy
Acute lymphoblastic leukemia
Castleman disease
Kikuchi-Fujimoto lymphadenitis
Single cell Multi-omics

Clinical Expertise

Hematopoietic neoplasms
Pathology of CAR T cell therapy in B-ALL

Education

M.B.B.S. (Medicine and Surgery), Madras Medical College, 2002
Ph.D. (Biomedical sciences, Immunology), University of Texas Southwestern Medical Center , 2007

Specialty Certification

American Board of Pathology (Anatomic and Clinical Pathology), 2013
American Board of Pathology (Hematology), 2014

Postgraduate Training

Compulsory Rotatory Residential Internship , Government General Hospital, Madras, India, 2001-2002
Post-Doctoral fellow of the National Multiple Sclerosis Society, Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, 2007-2009
Anatomic and Clinical Pathology Residency, Brigham and Women’s Hospital, Boston, MA, 2009-2013
Hematopathology , Brigham and Women’s Hospital, Dana Farber Cancer Institute and Boston
Children's Hospital Boston, MA, 2013-2014

Awards and Honors

Top 5 Poster Award in GSO Poster Competition, 2005
Graduate Student Organization (GSO) Travel Award, 2007
Eliot Goldings Award for the Best Graduate Student in Immunology, 2007
BWH Biomedical Research Institute Microgrant Award, 2012
Paul E. Strandjord Young Investigator Award from the Academy of Clinical Laboratory Physicians and Scientists, 2013
SIOP (International Society of Paediatric Oncology) Young Investigator Award, 2018
HTG EdgeSeq 2020 Autoimmune Panel Research Grant Award, 2020
Enid Gilbert Barness Prize - Society for Pediatric Pathology, 2022

Memberships and Professional Organizations

American Association of Immunologists, 2007 - 2009
Clinical Immunology Society, 2007 - 2009
United States and Canadian Academy of Pathology, 2011 - 2014
American Society for Clinical Pathology, 2012 - Present
Academy of Clinical Laboratory Physicians and Scientists, 2013 - 2015
Children's Oncology Group, 2015 - Present
International Clinical Cytometry Society, 2015 - present
Society for Hematopathology, 2015 - Present
Children's Oncology Group Young Investigator Mentorship Program, 2017 - Present
American Society for Clinical Oncology, 2018 - Present
College of American Pathologists Diagnostic Immunology Resource Committee, 2018 - Present
College of American Pathologists, 2018 - Present

Web Links


Selected Publications

Kikuchi-Fujimoto disease is mediated by an aberrant type I interferon response

Li EY, Xu J, Nelson ND, Teachey DT, Tan K, Romberg N, Behrens E, Pillai V, Modern Pathology 35(4): 462-469, 2022, PMID:34952944

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Transcriptome and unique cytokine microenvironment of castleman disease

Wing A, Xu J, Meng W, Rosenfeld AM, Li EY, Wertheim G, Paessler M, Bagg A, Frank D, Tan K, Teachey DT, Lim MS, Luning Prak E, Fajgenbaum DC, Pillai V, Modern Pathology 35(4): 451-461, 2022, PMID:34686774

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Pre-infusion factors impacting relapse immunophenotype following CD19 CAR T-cell

Lamble AJ, Myers RM, Taraseviciute A, John S, Yates B, Steinberg SM, Sheppard J, Kovach AE, Wood B, Borowitz MJ, Stetler-Stevenson M, Yuan CM, Pillai V, Foley T, Chung P, Chen L, Lee DW, Annesley C, DiNofia A, Grupp SA, Verneris MR, Gore L, Laetsch TW, Bhojwani D, Brown PA, Pulsipher MA, Rheingold SR, Gardner RA, Shah NN, Blood Advances, 2022, PMID:35482927

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Blinatumomab non-response and high disease burden are associated with inferior outcomes after CD19 CAR for B-ALL

Myers RM, Taraseviciute A, Steinberg SM, Lamble AJ, Sheppard J, Yates B, Kovach AE, Wood B, Borowitz MJ, Stetler-Stevenson M, Yuan CM, Pillai V, Foley T, Chung P, Chen L, Lee DW, Annesley C, DiNofia A, Grupp SA, John S, Bhojwani D, Brown PA, Laetsch TW, Gore L, Gardner RA, Rheingold SR, Pulsipher MA, Shah NN, Journal of Clinical Oncology 40(9): 932-944, 2022, PMID:34767461

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An erythematous indurated plaque on the neck of a 12-year-old girl

Xu Z, Wat M, Pillai V, Margolskee E, Rubin AI, Khurana MC, Pediatr Dermatol, 2022, PMID:35188291

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Initial (and incidental) diagnosis of plasma cell neoplasm in the liver and gastrointestinal tract- lessons to be learnt from two cases and literature review

Laczkó D, Pillai V, Frank D, Fortuna D, Human Pathology Reports, 2022

Haematology laboratory parameters to assess efficacy of CD19-, CD22-, CD33-, and CD123- directed chimeric antigen receptor T-cell therapy in haematological malignancies

Drumheller B, Gebre K, Lockhart B, Margolskee E, Obstfeld A, Paessler M, Pillai V, International Journal Of Laboratory Hematology, 2022

Bone Marrow Biopsy T Cell Aggregates and Cytokine Transcriptional Signatures Predict Sustained Response to CAR T-Cell Therapy in B-ALL

Lytle A, Faude S, Xu J, Pillai V, 63rd American Society of Hematology Annual Meeting and Exposition, 2021

A Novel FBXO45-Gef-H1 Axis Controls Oncogenic Signaling in B-Cell Lymphoma

Sahasrabuddhe AA, Chen X, Ma K, Wu R, Kapoor R, Chhipa RR, Zhang X, Onder O, Wilmore J, Gaudette BT, Pillai V, Li MM, Ahn JY, Chung F, Venkatesha Basrur PS, Conlon KP, Bailey NG, Hogaboam CM, Rottapel R, Kim J, Lopez C, Seufert J, Schlesner M, Siebert R, Cancro MP, Allman D, Pagano M, Staudt LM, Lim MS, Elenitoba-Johnson KSJ, 63rd American Society of Hematology Annual Meeting and Exposition, 2021

Bone Marrow Lymphoid Infiltrates and Aplasia after CD19-Directed CAR T Cell Therapy in Pediatric B-Lymphoblastic Leukemia

McFerran J, Lytle A, Gebre K, Pillai V, 63rd American Society of Hematology Annual Meeting and Exposition, 2021