PEOPLE

Vinodh Pillai, MD, PhD

Associate Professor of Pathology and Laboratory Medicine at the Children's Hospital of Philadelphia
Perelman School of Medicine at the University of Pennsylvania

Contact InformationChildren's Hospital of Philadelphia
Department of Pathology and Laboratory Medicine
Philadelphia, PA, 19104
Fax: 215-590-1736

Research Expertise

CAR T cell therapy
Acute lymphoblastic leukemia
Castleman disease
Kikuchi-Fujimoto lymphadenitis
Single cell sequencing of pediatric lymphoma
Spatial transcriptomics

Clinical Expertise

Hematopoietic neoplasms
Pathology of CAR T cell therapy in B-ALL

Education

M.B.B.S. (Medicine and Surgery), Madras Medical College, 2002
Ph.D. (Biomedical sciences, Immunology), University of Texas Southwestern Medical Center , 2007

Specialty Certification

American Board of Pathology (Anatomic and Clinical Pathology), 2013
American Board of Pathology (Hematology/Hematopathology), 2014

Postgraduate Training

Compulsory Rotatory Residential Internship , Government General Hospital, Madras, India, 2001-2002
Post-Doctoral fellow of the National Multiple Sclerosis Society, Immunology, University of Texas Southwestern Medical Center, Dallas, Texas, 2007-2009
Anatomic and Clinical Pathology Residency, Brigham and Women’s Hospital, Boston, MA, 2009-2013
Hematopathology , Brigham and Women’s Hospital, Dana Farber Cancer Institute and Boston
Children's Hospital Boston, MA, 2013-2014

Awards and Honors

Top 5 Poster Award in GSO Poster Competition, 2005
Graduate Student Organization (GSO) Travel Award, 2007
Eliot Goldings Award for the Best Graduate Student in Immunology, 2007
BWH Biomedical Research Institute Microgrant Award, 2012
Paul E. Strandjord Young Investigator Award from the Academy of Clinical Laboratory Physicians and Scientists, 2013
SIOP (International Society of Paediatric Oncology) Young Investigator Award, 2018
HTG EdgeSeq 2020 Autoimmune Panel Research Grant Award, 2020
Enid Gilbert Barness Prize - Society for Pediatric Pathology, 2022

Memberships and Professional Organizations

Clinical Immunology Society, 2007 - 2009
American Association of Immunologists, 2007 - 2009
United States and Canadian Academy of Pathology, 2011 - 2014
American Society for Clinical Pathology, 2012 - Present
Academy of Clinical Laboratory Physicians and Scientists, 2013 - 2015
Children's Oncology Group, 2015 - Present
International Clinical Cytometry Society, 2015 - present
Society for Hematopathology, 2015 - Present
Children's Oncology Group Young Investigator Mentorship Program, 2017 - Present
College of American Pathologists, 2018 - Present
American Society for Clinical Oncology, 2018 - Present
Perelman School of Medicine at the University of Pennsylvania, 2023 - 2023

Web Links


Selected Publications

Mapping the Cellular Biogeography of Human Bone Marrow Niches Using Single-Cell Transcriptomics and Proteomic Imaging

Bandyopadhyay S, Duffy M, Ahn KJ, Pang M, Smith D, Duncan G, Sussman J, Zhang I, Huang J, Lin Y, Xiong B, Imtiaz T, Chen C, Thadi A, Chen C, Xu J, Reichart M, Pillai V, Snaith O, Oldridge D, Bhattacharyya S, Maillard I, Carroll M, Nelson C, Qin L, Tan K, 65th ASH Meeting and Exposition, 2023

Transdifferentiation of B-lymphoblastic Leukemia to Histiocytic Sarcoma After Immunotherapy

Fenu E, Margolskee E, Pillai V, American journal of hematology 98(8): E216-E218, 2023, PMID:37259821

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Alternative Splicing of Its 5' UTR Limits CD20 mRNA Translation and Enables Resistance to CD20-directed Immunotherapies

Ang Z, Paruzzo L, Hayer KE, Schmidt C, Diz MT, Xu F, Zankharia U, Zhang Y, Soldan S, Zheng S, Falkenstein CD, Loftus JP, Yang SY, Asnani M, Sainos PK, Pillai V, Chong E, Li MM, Tasian SK, Barash Y, Lieberman PM, Ruella M, Schuster SJ, Thomas-Tikhonenko A, Blood, 2023

RAB27B Controls Palmitoylation Dependent NRAS Trafficking and Signaling in Leukemia

Ren J, Xing B, O’Keefe RA, Lv K, Wang R, Bauer K, Ghazaryan A, Burslem GM, Zhang J, O'Connell R, Pillai V, Hexner E, Philips M, Tong W, Journal of Clinical Investigation 133(12): e165510, 2023, PMID:37317963

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Pediatric Acute Erythroid Leukemias with Monocytic Antigen Expression and Novel Chromosomal Translocations

Zhu G, Inam Z, Calleroz A, Pillai V, Schore R, and Cheng J, Pediatric Blood & Cancer 19(): , 2023, PMID:37073602

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Proteogenomic Profiling of High-Grade B-Cell Lymphoma with 11q Aberration and Burkitt Lymphoma Reveals LEF1 as a Novel Biomarker

Hurwitz S, Lockhart B, Önder Ö, Wu R, Pillai V, Elenitoba-Johnson K, Lim MS, United States and Canadian Academy of Pathology 2023 New Orleans, Louisiana, 2023

Proteogenomic Profiling of High-Grade B-Cell Lymphoma with 11q Aberration and Burkitt Lymphoma Reveals LEF1 as a Novel Biomarker

Hurwitz S, Lockhart B, Önder Ö, Wu R, Sethi S, Aypar U, Siebert R, Dogan A, Pillai V, Elenitoba-Johnson K, Lim MS, Modern Pathology 36(7): , 2023, PMID:36997001

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Transcriptomics Reveal Genes and Pathways in Sinus Histiocytosis, Autoimmune Lymphoproliferative Syndrome and Rosai Dorfman Disease

Lockhart B, Vincent T, Paessler M, Pillai V, United States and Canadian Academy of Pathology 2023 New Orleans, Louisiana, 2023

Genes and Signaling Pathways Associated with Bone Marrow Fibrosis in B-Lymphoblastic Leukemia

Alnemri A, Lockhart B, Anil J, Baumgartner M, Pillai V, United States and Canadian Academy of Pathology 2023 New Orleans, Louisiana, 2023

Single Cell Multi-Omics Reveals Unique Populations, Cell Interactions and Signaling Pathways that Underlie Kikuchi-Fujimoto Disease

Pillai V, Smith D, Eichinger A, Seyedian A, Park CY, Tan K, Reizis B, United States and Canadian Academy of Pathology 2023 New Orleans, Louisiana, 2023