Eduardo D. Ruchelli, MD

Associate Professor of Pathology and Laboratory Medicine at the Children's Hospital of Philadelphia
University of Pennsylvania Perelman School of Medicine

Contact InformationDepartment of Pathology
Children's Hospital of Philadelphia
34th and Civic Center Blvd
Philadelphia, PA 19104
Office: 2155901728


Clinical Expertise

Pediatric Pathology (perinatal pathology and pediatric gastrointestinal and liver pathology)


M.D. University of Buenos Aires, Argentina, 1980

Specialty Certification

Anatomic Pathology/Clinical Pathology - American Board of Pathology, 1987
Pediatric Pathology - American Board of Pathology, 1990
American Board of Pathology
voluntary re-certification, 2014

Postgraduate Training

Ob/Gyn Resident, National Hospital, Buenos Aires, Argentina, 1981-1982
Pathology Resident, Department of Pathology, The Medical College of Pennsylvania, 1983-1987
Chief Resident, Department of Pathology, The Medical College of Pennsylvania, 1986-1987
Developmental/Pediatric Pathology Fellow, Children's Hospital of Pittsburgh and Magee-Women’s Hospital, 1987-1989

Awards and Honors

Academic Honors (Diploma de Honor), Class standing: upper 10%, 1980
Best paper presentation by a resident/fellow, Society for Pediatric Pathology interim meeting: "Correlation between ultrasound and pathologic examination in first trimester pregnancies", 1988

Memberships and Professional Organizations

US and Canadian Academy of Pathology, - Present
Society for Pediatric Pathology, - Present

Web Links

Selected Publications

Molecular and Immunohistochemical Analyses of the Focal Form of Congenital Hyperinsulinism

Suchi M, MacMullen C, Thornton PS, Adzick NS, Ganguly A, Ruchelli ED, Stanley CA., Mod Pathol 1(): 122-9, 2006

Preoperative evaluation of infants with focal or diffuse congenital hyperinsulinism by intravenous acute insulin response tests and selective pancreatic arterial calcium stimulation

Stanley CA., Thornton PS., Ganguly A., MacMullen C., Underwood P., Bhatia P., Steinkrauss L., Wanner L., Kaye R., Ruchelli E., Suchi M., Adzick NS., Journal of Clinical Endocrinology & Metabolism 89(1): 288-96, 2004

A multidisciplinary approach to the focal form of congenital hyperinsulinism leads to successful treatment by partial pancreatectomy

Adzick NS, Thornton PS, Stanley CA, Kaye R, Ruchelli E, J Pediatr Surg 39(): 270-5, 2004

Congenital hyperinsulinism: intraoperative biopsy interpretation can direct the extent of pancreatectomy

Suchi M, Thornton PS, Adzick NS, MacMullen C, Ganguly A, Stanley CA, Ruchelli ED, Am J Surg Pathol 28(10): , 2004

Histopathology of congenital hyperinsulinism: retrospective study with genotype correlations

Suchi M, MacMullen C, Thornton PS, Ganguly A, Stanley CA, Ruchelli E, Pediatr Dev Pathol 6(): 322-33, 2003, PMID:14692646

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Clinical and molecular characterization of a dominant form of congenital hyperinsulinism caused by a mutation in the high-affinity sulfonylurea receptor

Thornton PS., MacMullen C., Ganguly A., Ruchelli E., Steinkrauss L., Crane A., Aguilar-Bryan L., Stanley CA., Diabetes 52(9): 2403-10, 2003

Eosinophilic Esophagitis: A 10 year experience in 381 children

Liacouras CA, Spergel JM, Ruchelli E, Verma R, Mascarenhas M, Semeao E, Flick J, Kelly J, Brown-Whitehorn T, Mamula P, Markowitz J., Clin Gastroenterol Hepatol 3(): 1198-1206, 2005

Esophageal disorders in childhood (Chapter 2)

Ruchelli ED, Liacouras CA, Pathology of pediatric gastrointestinal and liver disease, 2004

Eosinophilic esophagitis

Liacouras CA, Ruchelli E, Curr Opin Pediatr 16(): 560-566, 2004, PMID:15367851

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Pollen and eosinophilic esophagitis

Fogg MI., Ruchelli E., Spergel JM., Journal of Allergy & Clinical Immunology 112(4): 796-7, 2003

Pathology of pediatric gastrointestinal and liver disease

Russo P, Ruchelli ED, Piccoli DA (eds), , 2004

Primary eosinophilic esophagitis in children: succesful treatment with oral corticosteroids.

Liacouras CA, Wenner WJ, Brown K, Ruchelli E, J Pediatr Gastroenterol Nutr 26(): 380-385, 1998

Severity of esophageal eosinophilia predicts response to conventional gastroesophageal reflux therapy.

Ruchelli E., Voytek T., Wenner W., Brown K., Liacouras C, Pediatr Develop Pathol 2(): 15-18, 1999