Timothy Chao, MD, PhD
Assistant Professor of Clinical Pathology and Laboratory MedicinePerelman School of Medicine at the University of Pennsylvania
Contact Information801 Spruce Street
10th Floor Spruce Building
Philadelphia, PA, 19107
Fax: 215-829-7564
Specialty Division
Anatomic Pathology
Education
BS (Bioengineering), University of Washington, 2008
BA (Biochemistry), University of Washington, 2008
PhD (Philosophy), Perelman School of Medicine at the University of Pennsylvania, 2017
MD (Doctor of Medicine), Perelman School of Medicine at the University of Pennsylvania, 2019
Specialty Certification
American Board of Pathology, 2023
Postgraduate Training
Resident, Anatomic and Clinical Pathology, Thomas Jefferson University Hospital, 2019-2023
Gastrointestinal and Liver Pathology Fellow, University of Pennsylvania Health System, 2023-2024
Awards and Honors
Dean's List/University of Washington, 2003-2008
UW Honors General Chemistry Achievement Award/University of Washington, 2004-2004
UW College of Engineering's Clayton and Helen Danner Endowed Scholarship/University of Washington, 2006-2007
Mary Gates Research Scholarship/University of Washington, 2006-2007
Stowell-Orbison Certificate of Merit, United States and Canadian Academy of Pathology (USCAP) Honors
Awarded 2020 & 2021, 2020-2021
Department of Pathology and Genomic Resident Scholar Award/Thomas Jefferson University Hospital, 2023-2023
Memberships and Professional Organizations
Pathology Society of Philadelphia, 2022 - Present
Web Links
Selected Publications
A rare metastatic mesenteric malignant PEComa with TSC2 mutation treated with palliative surgical resection and nab-sirolimus: a case report
Meredith L, Chao T, Nevler A, Basu Mallick A, Singla RK, McCue PA, Bowne WB, Jiang W., Diagnostic Pathology 18(1): 45, 2023, PMID:37041531
Modern Blood Culture: Management Decisions and Method Options
M.D. Gonzalez, T. Chao, M.A. Pettengill, Clinics in Laboratory Medicine 40(4): 379-392, 2020, PMID:33121610
PD-L1 positivity associated with presence of tertiary lymphoid structures and high-stage disease in upper tract urothelail carcinoma
M.E. Smith, S.J. Farahani, T. Chao, M. Palmer, A. Arriola, P. Lal, American Journal of Clinical Pathology 154(6): 802-810, 2020, PMID:32864684
Subependymal giant cell astrocytoma without clinically or genetically identifiable tuberous sclerosis complex: a case report.
K. Hafazalla, D.Y. Ye, T. Chao, M. Curtis, C.J. Farrell, Case Reports and Series in Surgery 1(2): 1-4, 2020
CSF Cytokine Profiles Help Discriminate CNS Tumors, Lymphomas, Autoimmune Diseases, and Infections
T. Chao, D. Fortuna, R. Kean, D. Hooper, M. Nagurney, M. Curtis., Laboratory Investigation 100(Suppl 1): 1605, 2020
Tumor cell-intrinsic factors underlie heterogeneity of immune cell infiltration and response to immunotherapy.
J. Li, K.T. Byrne, F. Yan, T. Yamazoe, Z. Chen, T. Baslan, L.P. Richman, J.H. Lin, Y.H. Sun, A.J. Rech, D. Balli, C.A. Hay, Y. Sela, A.J. Merrell, S.M. Liudahl, N. Gordon, R.J. Norgard, S. Yuan, S. Yu, T. Chao, S. Ye, TS.K. Eisinger-Mathason, R.B. Faryabi, J.W. Tobias, S.W. Lowe, L.M. Coussens, E.J. Wherry, R.H. Vonderheide, B.Z. Stanger, Immunity 49(1): 178-193.e7., 2018, PMID:29958801
Cancer-associated fibroblasts neutralize the anti-tumor effect of CSF1 receptor blockade by inducing PMN-MDSC infiltration of tumors
V. Kumar, L. Donthireddy, D. Marvel, T. Condamine, F. Wang, S. Lavilla-Alonso, A. Hashimoto, P. Vonteddu, R. Behera, M.A. Goins, C. Mulligan, B. Nam, N. Hockstein, F. Denstman, S. Shakamuri, D.W. Speicher, A.T. Weeraratna, T. Chao, R.H. Vonderheide, L.R. Languino, P. Ordentlich, Q. Liu, X. Xu, A. Lo, E. Pure, C. Zhang, A. Loboda, M.A. Sepulveda, L.A. Snyder, D.I. Gabrilovich., Cancer Cell 32(5): 654-668, 2017, PMID:29136508
CXCR2-dependent accumulation of tumor-associated neutrophils regulates T-cell immunity in pancreatic ductal adenocarcinoma
T. Chao, E.E. Furth, R.H. Vonderheide, Cancer Immunology Research 4(11): 968-982, 2016, PMID:27737879
Lack of immunoediting in murine pancreatic cancer reversed with neoantigen
R. Evans, M. Diamond, A. Rech, T. Chao, M. Richardson, J. Lin, D. Bajor, K. Byrne, B. Stanger, J. Riley, N. Markosyan, R. Winograd, R.H.Vonderheide, Journal of Clinical Investigation Insight 1(14): e88328, 2016, PMID:27642636
An Autoimmune Response Signature Associated with the Development of Triple-Negative Breast Cancer Reflects Disease Pathogenesis
H. Katayama, C. Boldt, J.J. Ladd, M.M. Johnson, T. Chao, M. Capello, J. Suo, J. Mao, J.E. Manson, R. Prentice, F. Esteva, H. Wang, M.L. Disis, S. Hanash., Cancer Research 75(16): 3246-54, 2015, PMID:26088128