Jennifer E. Pogoriler, MD, PhD
Associate Professor of Pathology and Laboratory Medicine at the Children's Hospital of PhiladelphiaPerelman School of Medicine at the University of Pennsylvania
Contact InformationThe Children's Hospital of Philadelphia
Department of Pathology and Laboratory Medicine
3401 Civic Center Boulevard
5th Floor Main Building Suite 5NW13
Philadelphia, PA 19104
Fax: 215590-1736
Email: pogorilerj@chop.edu
Education
BA (Biology), Williams College, 1999
PhD (Cancer Biology), University of Chicago, 2006
MD (Medicine), University of Chicago, 2008
Specialty Certification
The American Board of Pathology - Anatomic and Clinical Pathology, 2012
The American Board of Pathology - Pediatric Pathology, 2014
Postgraduate Training
Anatomic and Clinical Pathology, University of Chicago Medical Center Department of Pathology, Chicago IL, 2008-2012
Thoracic and Surgical Pathology, University of Chicago Medical Center, Department of Pathology, Chicago IL, 2012-2013
Pediatric Pathology, Boston Children's Hospital, Boston MA, 2013-2014
Awards and Honors
BA in Biology with Highest Honors, Summa Cum Laude, Erastus C. Benedict 1st prize in Biology, 1999
Phi Beta Kappa, Sigma Xi, 1999
American Society for Clinical Pathology Award for Academic Excellence and Achievement, 2002
Departmental Award for Outstanding Performance in the General Field of Pathology, 2008
Alpha Omega Alpha, Beta chapter, 2008
MD Graduation with honors, 2008
Chief Resident, 2011
Society for Pediatric Pathology Enid Gilbert Barness Prize, 2024
Memberships and Professional Organizations
The Chicago Pathology Society, 2009 - 2013
United States & Canadian Academy of Pathology, 2010 - Present
College of American Pathologists, 2010 - 2013
American Society for Clinical Pathology, 2010 - 2013
Society for Pediatric Pathology, 2012 - Present
Pulmonary Pathology Society, 2014 - Present
Children's Oncology Group, 2019 - Present
Children's Interstitial and Diffuse Lung Disease Foundation, 2021 - Present
TBX4 International Scientific Consortium, 2022 - Present
The Pediatric Pulmonary Hypertension Network Pathology Consortium, 2023 - Present
International Pleuropulmonary Blastoma Registry, 2024 - Present
Web Links
Selected Publications
A humanized anaplastic lymphoma kinase (ALK)-directed antibody-drug conjugate with pyrrolobenzodiazepine payload demonstrates efficacy in ALK-expressing cancers
Guerra AD, Matkar S, Acholla C, Casey C, Li G, Mazzeschi M, Patel K, Krytska K, Chen C, Balyasny S, Kalna J, Kamitsuka P, Gerelus M, Polkosnik G, Groff D, Mukherje A, Adams C, Witek G, Hamilton AK, Martinez D, Pogoriler J, Spear TT, Li Y, Jung P, Alvarado D, Lauriola M, Maris JM, Wolpaw AJ, Bosse KR, Dimitrov D, Mir M, Jelev DV, Mossé YP, Nat Commun 16(11): , 2025, PMID:40813394
Identification of the Notch ligand DLK1 as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma
Sun NY, Kumar S, Kim YS, Varghese D, Mendoza A, Nguyen R, Okada R, Reilly K, Widemann B, Pommier Y, Elloumi F, Dhall A, Taniyama D, Patel M, Aber E, Contreras CF, Kaplan RN, Kiseljak-Vassiliades K, Wierman ME, Martinez D, Pogoriler J, Hamilton AK, Diskin SJ, Maris JM, Robey RW, Gottesman MM, Del Rivero J, Roper N., Nat Commun 16(1): , 2025, PMID:40595495
Congenital Cystic Lung Lesions: An Update on Clinical and Pathologic Correlates
Nelson, ND and Pogoriler, J, Surgical Pathology Clinics, 2025
Congenital Peribronchial Myofibroblastic Tumors Harbor a Recurrent EGFR Kinase Domain Duplication
Younes S, Suarez CJ, Pogoriler J, Bhatti T, Shenoy A, Saab R, Surrey LF, Tan SY., Modern Pathology 38(): 100661, 2025, PMID:39577666
Complex Pediatric Neoplasms: The Role of Congenital Cardiothoracic Surgery
Lindsay J. Nitsche, Colleen E. Bontrager, Paul J. Devlin, Lea F. Surrey, Jennifer E. Pogoriler, Portia A. Kreiger, Theodore W. Laetsch, Frank Balis, Alexander S. Fairman, Peter Mattei, Stephanie M. Fuller, JTCVS Techniques, 2025
Cystic masses of the pediatric lung: update on congenital pulmonary airway malformation and its differential diagnosis
Pogoriler J, Vargas SO, Virchows Arch 486(): 177-188, 2025, PMID:39741212
Interleukin-15-armoured GPC3 CAR T cells for patients with solid cancers.
Steffin D, Ghatwai N, Montalbano A, Rathi P, Courtney AN, Arnett AB, Fleurence J, Sweidan R, Wang T, Zhang H, Masand P, Maris JM, Martinez D, Pogoriler J, Varadarajan N, Thakkar SG, Lyon D, Lapteva N, Zhuyong M, Patel K, Lopez-Terrada D, Ramos CA, Lulla P, Armaghany T, Grilley BJ, Gottschalk S, Dotti G, Metelitsa LS, Heslop HE, Brenner MK, Sumazin P, Heczey A, Nature 637(): 940-946, 2025, PMID:39604730
Anaplastic Lymphoma Kinase Inhibition Therapy for Hereditary Neuroblastoma
Mossé YP, Polkosnik G, Pogoriler J, Mattei P, States LJ, Maris JM., JCO Precis Oncol, 2025, PMID:40294355
Pediatric Diffuse Lung Disease in Infants: Imaging Findings and Histopathologic Correlation
Karen I. Ramirez-Suarez, MD • Santiago Martinez-Correa, MD • Luis O. Tierradentro-Garcia, MD • Ammie M. White, MD • Mariangeles Medina Perez, MD Hansel J. Otero, MD • David M. Biko, MD • Lisa R. Young, MD • Jennifer Pogoriler, MD, PhD • John P. Lichtenberger, MD • Jordan B. Rapp, MD, RadioGraphics 44(11): e240022, 2024, PMID:39418186
A proteogenomic surfaceome study identifies DLK1 as an immunotherapeutic target in neuroblastoma
Hamilton AK, Radaoui AB, Tsang M, Martinez D, Conkrite KL, Patel K, Sidoli S, Delaidelli A, Modi A, Rokita JL, Lane MV, Hartnett N, Lopez RD, Zhang B, Zhong C, Ennis B, Miller DP, Brown MA, Rathi KS, Raman P, Pogoriler J, Bhatti T, Pawel B, Glisovic-Aplenc T, Teicher B, Erickson SW, Earley EJ, Bosse KR, Sorensen PH, Krytska K, Mosse YP, Havenith KE, Zammarchi F, van Berkel PH, Smith MA, Garcia BA, Maris JM, Diskin SJ, Cancer Cell 42(11): 1970-1982, 2024, PMID:39454577
