The latest results of studies involving both adults and children with advanced blood cancers that have failed to respond to standard therapies.
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Robert W. Doms, MD, PhD, professor of Pathology and Laboratory Medicine at the Perelman School of Medicine and pathologist-in-chief and chair of Pathology and Laboratory Medicine at The Children’s Hospital of Philadelphia, is one of five faculty members from the University of Pennsylvania who have been named fellows of the American Association for the Advancement of Science (AAAS).
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The lab of Avinash Bhandoola, MBBS, PhD, recently published a paper in Nature Immunology "T cell development requires constraint of the myeloid regulator C/EBP-a by the Notch target and transcriptional repressor Hes1." Notch signaling induces expression of genes that promote the maturation of T cells and discourage alternative cell fates. Hematopoietic deficiency in the Notch target Hes1 results in severe T cell lineage defects, but the underlying mechanism is unknown.
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The peer-reviewed journal Human Gene Therapy is celebrating its 25th anniversary in 2014 by publishing a series of Perspectives by top researchers in the field of cell and gene therapy. Five "Pioneer" scientists from the Perelman School of Medicine at the University of Pennsylvania are among the 21 investigators who will be honored throughout the next 12 months.
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The Academy of Master Clinicians was launched in 2013 to recognize those Penn Medicine clinicians who exemplify the highest standards of clinical excellence, humanism and professionalism.
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Nina Luning Prak, MD, PhD, Associate Professor of Pathology and Laboratory Medicine, is the 2013 recipient of the Lady Barbara Colyton Award for Autoimmune Research, which recognizes outstanding research in the field of autoimmune diseases. Dr. Luning Prak, who works on the genetics of the antibody repertoire in autoimmunity, was selected as the sixteenth recipient of the 2013 Colyton Award as part of the annual Perelman School of Medicine Awards of Excellence.
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Gerard Schellenberg, PhD, director of the Alzheimer’s Disease Genetics Consortium (ADGC) and professor of Pathology and Laboratory Medicine in the Perelman School of Medicine at the University of Pennsylvania, is the co-senior author of a global collaboration that has found 11 new genetic areas of interest that contribute to late-onset Alzheimer's Disease (LOAD).
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Malek Kamoun, MD, PhD, has been elected President-Elect of the American Society for Histocompatibility and Immunogenetics.
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A $1.5 million gift to the University of Pennsylvania has established the Barbara and Edward Netter Associate Professorship in Cancer Gene Therapy at the Abramson Cancer Center. Bruce Levine, PhD, a faculty member in the department of Pathology and Laboratory Medicine in the Perelman School of Medicine and the director of the Clinical Cell and Vaccine Production Facility, has been appointed to the Barbara and Edward Netter Associate Professor in Cancer Gene Therapy.
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Department faculty members Don Siegel, PhD, MD, and David B. Roth, MD, PhD, were speakers at the Inaugural Annual Blood Center Symposium at the Penn-CHOP Blood Center for Patient Care and Discovery on Tuesday, October 8, 2013. Their symposium lectures were on the evolving roles of transfusion medicine and cellular engineering for hematologic disorders and on personalized medicine for patients with blood disorders, respectively.
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