Cherry Lab
The Cherry Lab is interested in emerging and globally important arthropod-borne viruses including the three major families that infect humans: the flaviviruses, alphaviruses and bunyaviruses. The Lab uses chemical and genetic screening technologies to perform a wide array of cell-based screens in human and insect cells studying emerging RNA viruses.
Principal Investigator: Sara Cherry, PhD
Partial ORF1ab Gene Target Failure with Omicron BA.2.12.1
Rodino KG, Peaper DR, Kelly BJ, Bushman F, Marques A, Adhikari H, Tu ZJ, Marrero Rolon R, Westblade LF, Green DA, Berry GJ, Wu F, Annavajhala MK, Uhlemann AC, Parikh BA, McMillen T, Jani K, Babady NE, Hahn AM, Koch RT, Grubaugh ND; Yale SARS-CoV-2 Genomic Surveillance Initiative, Rhoads DD. J Clin Microbiol. 2022 May 18:e0060022. doi: 10.1128/jcm.00600-22. Online ahead of print. PMID: 35582905
Subcellular Detection of SARS-CoV-2 RNA in Human Tissue Reveals Distinct Localization in Alveolar Type 2 Pneumocytes and Alveolar Macrophages
Acheampong KK, Schaff DL, Emert BL, Lake J, Reffsin S, Shea EK, Comar CE, Litzky LA, Khurram NA, Linn RL, Feldman M, Weiss SR, Montone KT, Cherry S, Shaffer SM.
mBio. 2022 Feb 8:e0375121. doi: 10.1128/mbio.03751-21. Online ahead of print.
Femtomolar SARS-CoV-2 Antigen Detection Using the Microbubbling Digital Assay with Smartphone Readout Enables Antigen Burden Quantitation and Tracking
Chen H, Li Z, Feng S, Richard-Greenblatt M, Hutson E, Andrianus S, Glaser LJ, Rodino KG, Qian J, Jayaraman D, Collman RG, Glascock A, Bushman FD, Lee JS, Cherry S, Fausto A, Weiss SR, Koo H, Corby PM, Oceguera A, O'Doherty U, Garfall AL, Vogl DT, Stadtmauer EA, Wang P. Clin Chem. 2021 Aug 12:hvab158. doi: 10.1093/clinchem/hvab158. Online ahead of print.
Seasonal human coronavirus antibodies are boosted upon SARS-CoV-2 infection but not associated with protection
Elizabeth M Anderson, Eileen C Goodwin, Anurag Verma, Claudia P Arevalo, Marcus J Bolton, Madison E Weirick, Sigrid Gouma, Christopher M McAllister, Shannon R Christensen, JoEllen Weaver, Phillip Hicks, Tomaz B Manzoni, Oluwatosin Oniyide, Holly Ramage, Divij Mathew, Amy E Baxter, Derek A Oldridge, Allison R Greenplate, Jennifer E Wu, Cécile Alanio, Kurt D'Andrea, Oliva Kuthuru, Jeanette Dougherty, Ajinkya Pattekar, Justin Kim, Nicholas Han, Sokratis A Apostolidis, Alex C Huang, Laura A Vella, E John Wherry, Nuala J Meyer, Sara Cherry, Paul Bates, Daniel J Rader, Scott E Hensley. Cell. Available online 9 February 2021. doi: https://doi.org/10.1016/j.cell.2021.02.010
John W. Eckman Professor of Medical Science
Professor of Microbiology
Professor of Microbiology in Biochemistry and Biophysics
Scientific Director, High-Throughput Screening Core
Director, Program for Chemogenomic Discovery
Perelman School of Medicine at the University of Pennsylvania
Assistant Professor of Pathology and Laboratory Medicine
Assistant Professor of Microbiology
Perelman School of Medicine at the University of Pennsylvania
Distinct microbiological signatures associated with triple negative breast cancer
Banerjee S, Wei Z, Tan F, Peck KN, Shih N, Feldman M, Rebbeck TR, Alwine JC, Robertson ES.
Sci Rep. 2015 Oct 15;5:15162. doi: 10.1038/srep15162
Associate Professor of Clinical Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Director, Clinical Microbiology Laboratory
Co-Director, HUP/CHOP Fellowship in Clinical Microbiology
Associate Program Director for Clinical Pathology, HUP Pathology Residency Program
