Long noncoding RNA LINP1 regulates repair of DNA double-strand breaks in triple-negative breast cancer
Zhang Y, He Q, Hu Z, Feng Y, Fan L, Tang Z, Yuan J, Shan W, Li C, Hu X, Tanyi JL, Fan Y, Huang Q, Montone K, Dang CV, Zhang L. Nat Struct Mol Biol. 2016 Apr 25. | doi: 10.1038/nsmb.3211
RAG2 and XLF/Cernunnos interplay reveals a novel role for the RAG complex in DNA repair
Lescale C, Abramowski V, Bedora-Faure M, Murigneux V, Vera G, Roth DB, Revy P, de Villartay JP, Deriano L. Nat Commun. 2016 Feb 2;7:10529. | doi: 10.1038/ncomms10529
Off-Target V(D)J Recombination Drives Lymphomagenesis and Is Escalated by Loss of the Rag2 C Terminus
Mijušković M, Chou YF, Gigi V, Lindsay CR, Shestova O, Lewis SM, Roth DB. Cell Rep. 2015 Sep 10 [Epub ahead of print] doi: 10.1016/j.celrep.2015.08.034
Faryabi Lab
Genome-wide signatures of replicative stress and the contributions of replication stress-induced genomic lesions to hematological malignancies
Principal Investigator: Robert Babak Faryabi, PhD
Perelman School of Medicine at the University of Pennsylvania
Associate Professor of Pathology and Laboratory Medicine
Assistant Professor of Cancer Biology
Perelman School of Medicine at the University of Pennsylvania
Bassing Lab
DNA repair, genomic instability, cancer, lymphocyte development, V(D)J recombination, class switch recombination, auto-immunity
Principal Investigator: Craig H. Bassing, PhD
Weitzman Lab
Virology, Virus Replication, DNA Damage and Repair, Genome Instability, Viral Vectors
Principal Investigator: Matthew D. Weitzman, PhD
Johnson Lab
Molecular biology of aging, cell senescence, Werner syndrome, telomeres,
recombination, G-quadruplexes, neurodegeneration, transplantation.
Principal Investigator: F. Bradley Johnson, MD, PhD
Professor of Microbiology, Professor of Pathology and Laboratory Medicine
University of Pennsylvania Perelman School of Medicine
