Lambris Lab
The Lambris Lab consists of an international and interdisciplinary team that investigates the various aspects of innate immunity, and particularly the complement system, in health and disease. The integrated research approach encompasses projects such as the quantitative analysis of protein-protein interactions of complement components, the development of therapeutic complement inhibitors (e.g. Compstatin), complement evasion by human pathogens, and the role of complement in liver regeneration and cancer development.
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Professor of Pathology and Laboratory Medicine at the
Hospital of the University of Pennsylvania
Director, Clinical Immunology and Histocompatibility Laboratory
Perelman School of Medicine at the University of Pennsylvania
Contact Information
Hospital of the University of Pennsylvania
7.020 Founders Pavilion
3400 Spruce Street
Philadelphia, PA 19104-4238
Tel: 215-614-1902
Fax: 215-349-5090
Email: malekkam@pennmedicine.upenn.edu
Research Expertise
Research Interests: HLA genes and molecules in clinical transplantation
Keywords: Human immunogenetics, HLA genes and molecules. Clinical Histocompatibility, clinical transplantation, autoimmunity.
Research Summary:
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Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Associate Vice Chair for Research
Department of Pathology and Laboratory Medicine
Contact Information
Perelman School of Medicine at the University of Pennsylvania
Department of Pathology and Laboratory Medicine
John Morgan Building, Rm. 288
3620 Hamilton Walk
Philadelphia, PA 19104
Email: kambayat@pennmedicine.upenn.edu
Research Expertise
Research Interests: Regulation of T cell responses, signal transduction, regulatory T cell expansion and homeostasis, regulation of skin barrier function
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Professor of Pathology and Laboratory Medicine
Professor of Microbiology
Perelman School of Medicine at the University of Pennsylvania
Chair and Pathologist-in-Chief
Children's Hospital of Philadelphia
Contact Information
Children’s Hospital of Philadelphia
Department of Pathology and Laboratory Medicine
Main Building, 5th Floor, Rm. 5135
34th St. & Civic Center Blvd.
Philadelphia, PA 19104
Tel: 215-590-4446
Fax: 215-590-1021
Email: domsr@email.chop.edu
Research Expertise
Research Interests:
HIV; emerging viral pathogens
Keywords:
HIV; Rift Valley fever virus; virus-host cell interactions; Andes virus
Description of Research:
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Professor of Pathology and Laboratory Medicine
Professor of Medicine
Perelman School of Medicine at the University of Pennsylvania
Attending Physician, Coagulation Laboratory
Contact Information
Perelman School of Medicine at the University of Pennsylvania
Department of Pathology and Laboratory Medicine
Stellar-Chance Laboratories, Rm. 513A
422 Curie Blvd.
Philadelphia, PA 19104
Email: dcines@pennmedicine.upenn.edu
Research Expertise
Thrombosis, fibrinolysis, vascular biology, immunohematology
Clinical Expertise
Coagulation, immune hematological disorders
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Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Contact Information
Children's Hospital of Philadelphia
Department of Pathology and Laboratory Medicine
Abramson Pediatric Research Center, Rm. 816D
3615 Civic Center Boulevard
Philadelphia, PA 19104
Tel: 267-426-5410
Fax: 267-426-5165
Email: jburkhar@pennmedicine.upenn.edu
Research Expertise
Regulation of cytoskeletal dynamics in T cells and dendritic cells, and cytoskeletal control of the immune response
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Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
Perelman School of Medicine at the University of Pennsylvania
Contact Information
Hospital of the University of Pennsylvania
Department of Pathology and Laboratory Medicine
Founders Building, Rm. 6.042
3400 Spruce St.
Philadelphia, PA 19104
Tel: 215-662-6538
Email: kumarasen.cooper@pennmedicine.upenn.edu
Global Health Expertise
Penn Pathology Residents Electives at UB, Gaborone:
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Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Contact Information
Children’s Hospital of Philadelphia
Colket Translational Research Building, Rm. 4054
3501 Civic Center Boulevard
Philadelphia, PA 19104
Tel: 267-426-0311
Email: bassing@pennmedicine.upenn.edu
Research Interests: Elucidate genetic, epigenetic, and biochemical mechanisms by which mammals develop their immune systems while suppressing autoimmunity and genomic aberrations that cause leukemia or lymphoma.
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The National Institute of Allergy and Infectious Diseases (NIAID) has awarded a five-year, $10 million renewal of a program project to study the oldest part of the human immune system, the complement system.
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Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Contact Information
Department of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
John Morgan Building, Rm. 230
3620 Hamilton Walk
Philadelphia, PA 19104
Office: 215-746-5547
Fax: 215-573-2350
Email: dallman@pennmedicine.upenn.edu
Research Interests:
Plasma cell differentiation, B cell development
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