A new study published in Nature Communications finds that a mutation in the ATRX gene, a potential molecular marker for aggressive brain tumors, can also serve as a much-needed biomarker for rare neuroendocrine tumors.
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New technique to repurpose fibroblasts into functional melanocytes.
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"Therapeutic C3 inhibitor Cp40 abrogates complement activation induced by modern hemodialysis filters" published in Immunobiology.
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Lambris Lab
The Lambris Lab consists of an international and interdisciplinary team that investigates the various aspects of innate immunity, and particularly the complement system, in health and disease. The integrated research approach encompasses projects such as the quantitative analysis of protein-protein interactions of complement components, the development of therapeutic complement inhibitors (e.g. Compstatin), complement evasion by human pathogens, and the role of complement in liver regeneration and cancer development.
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Professor of Pathology and Laboratory Medicine
Director, Penn Neurodegeneration Genomics Center
Perelman School of Medicine at the University of Pennsylvania
Contact Information
Department of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Stellar-Chance Laboratories, Room 609B
422 Curie Blvd.
Philadelphia, PA 19104
Email: gerardsc@pennmedicine.upenn.edu
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Dr. Ralph and Sallie Weaver Professor of Research Medicine
Perelman School of Medicine at the University of Pennsylvania
Contact Information
Perelman School of Medicine at the University of Pennsylvania
Department of Pathology and Laboratory Medicine
Stellar-Chance Laboratories, Rm. 401
422 Curie Boulevard
Philadelphia, PA 19104
Tel: 215-746-5765
Fax: 215-573-8738
Email: lambris@pennmedicine.upenn.edu
Research Expertise
Complement, Inflammation, Cancer, Systems Biology, Therapeutics, Peptides, Innate Immunity, liver regeneration, sepsis
Research Summary:
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Professor of Pathology and Laboratory Medicine at the
Hospital of the University of Pennsylvania
Director, Clinical Immunology and Histocompatibility Laboratory
Perelman School of Medicine at the University of Pennsylvania
Contact Information
Hospital of the University of Pennsylvania
7.020 Founders Pavilion
3400 Spruce Street
Philadelphia, PA 19104-4238
Tel: 215-614-1902
Fax: 215-349-5090
Email: malekkam@pennmedicine.upenn.edu
Research Expertise
Research Interests: HLA genes and molecules in clinical transplantation
Keywords: Human immunogenetics, HLA genes and molecules. Clinical Histocompatibility, clinical transplantation, autoimmunity.
Research Summary:
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Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Associate Vice Chair for Research
Department of Pathology and Laboratory Medicine
Contact Information
Perelman School of Medicine at the University of Pennsylvania
Department of Pathology and Laboratory Medicine
John Morgan Building, Rm. 288
3620 Hamilton Walk
Philadelphia, PA 19104
Email: kambayat@pennmedicine.upenn.edu
Research Expertise
Research Interests: Regulation of T cell responses, signal transduction, regulatory T cell expansion and homeostasis, regulation of skin barrier function
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Professor of Pathology and Laboratory Medicine
Professor of Microbiology
Perelman School of Medicine at the University of Pennsylvania
Chair and Pathologist-in-Chief
Children's Hospital of Philadelphia
Contact Information
Children’s Hospital of Philadelphia
Department of Pathology and Laboratory Medicine
Main Building, 5th Floor, Rm. 5135
34th St. & Civic Center Blvd.
Philadelphia, PA 19104
Tel: 215-590-4446
Fax: 215-590-1021
Email: domsr@email.chop.edu
Research Expertise
Research Interests:
HIV; emerging viral pathogens
Keywords:
HIV; Rift Valley fever virus; virus-host cell interactions; Andes virus
Description of Research:
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Associate Professor of Pathology and Laboratory Medicine at Children's Hospital of Philadelphia
Perelman School of Medicine at the University of Pennsylvania
Director, Division of Genomic Diagnostics
Children's Hospital of Philadelphia (CHOP)
Contact Information
Children’s Hospital of Philadelphia
Department of Pathology and Laboratory Medicine
Abramson Pediatric Research Center, Rm. 716C
3615 Civic Center Blvd.
Philadelphia, PA 19104
Tel: 267-426-7885
Email: conlinl@email.chop.edu
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