Content tagged "research":

Laura K. Conlin, PhD, FACMG

Associate Professor of Pathology and Laboratory Medicine at Children's Hospital of Philadelphia
Perelman School of Medicine at the University of Pennsylvania 

Director, Division of Genomic Diagnostics
Children's Hospital of Philadelphia (CHOP)

Douglas B. Cines, MD

Professor of Pathology and Laboratory Medicine
Professor of Medicine
Perelman School of Medicine at the University of Pennsylvania 

Attending Physician, Coagulation Laboratory

Janis K. Burkhardt, PhD
Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Kurt R. Brunden, PhD

Research Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania

Director of Drug Discovery
Center for Neurodegenerative Disease Research

Craig H. Bassing, PhD
Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Bruce L. Levine, PhD

Barbara and Edward Netter Professor in Cancer Gene Therapy
Perelman School of Medicine at the University of Pennsylvania

Founding Director, Clinical Cell and Vaccine Production Facility (CVPF)

Khalil Bdeir, PhD

Research Associate Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania

David Michael Allman, PhD

Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania

Vice Chair for Faculty Development and Academic Affairs
Department of Pathology and Laboratory Medicine

The Department of Pathology and Laboratory Medicine has a long history of supporting both clinical and translational research. In addition, the wide scope of expertise of its faculty is available to provide support for scientific research projects, as participants in diagnostic procedures or infusional therapeutics, as consultants, or as co-investigators.

Research at Penn

Translational and basic-science research in the Department of Pathology and Laboratory Medicine at Penn is conducted in many areas, including Autoimmunity and Allergy, Bioinformatics, Cancer Biology, Cell Biology and Signal Transduction, Developmental Mechanisms, Developmental, Stem Cell, & Regenerative Biology, Diagnostic Innovation, Experimental Therapeutics, Gene Therapy and Vaccines, Genetics and Gene Regulation, HIV, Immune Health, Immunology and Immunobiology, Immunotherapy, Microbiology, Neurodegenerative Diseases, Proteomics, Recombination, Class Switching, DNA Repair.

Highlights

Research Summary

Research in the Department of Pathology and Laboratory Medicine at Penn is one of the three core missions and encompasses many areas of expertise. Major focused strengths and scientific synergies have emerged within the Department in recent years, and as such, the Department’s research efforts have been organized into three broadly defined scientific divisions: the Division of Cancer and Immunobiology, the Division of Neuropathology/Neurodegeneration, and the Division of Diagnostic Innovation.

With a longstanding research focus on fundamental biophysical aspects of diseases, the Department is one of the few places where the basic science divisions and clinical practices are still linked, thus bridging the medical school and health services. Resulting advantages to both include providing resources, intellectual and financial; fostering translational research; ensuring that basic science observations are applied towards patient treatment and diagnosis; and establishing accessibility and dialogue between clinicians and basic scientists. As part of the Raymond and Ruth Perelman School of Medicine at the University of Pennsylvania, the Department is consistently among the nation's top recipients of funding for biomedical research from the National Institutes of Health (NIH). 


Research Initiatives

  • intracellular signaling
  • molecular mechanisms of leukemogenesis and sarcomagenesis, with special emphasis on aberrant transcriptional factors; RNA pathobiology
  • cellular development, such as lymphocyte, melanocyte, and bone development
  • endothelial cell and platelet pathobiology
  • metastasis and behavior of cells in situ and in three-dimensions
  • proteomics and protein modeling
  • emerging infectious diseases, including HIV
  • neurodegenerative mechanisms
  • experimental therapeutics

 

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