isoCirc catalogs full-length circular RNA isoforms in human transcriptomes
Xin R, Gao Y, Gao Y, Wang R, Kadash-Edmondson KE, Liu B, Wang Y, Lin L, Xing Y. isoCirc catalogs full-length circular RNA isoforms in human transcriptomes. Nat Commun. 2021 Jan 12;12(1):266. doi: 10.1038/s41467-020-20459-8.
Targeted massively parallel sequencing of mature lymphoid neoplasms: assessment of empirical application and diagnostic utility in routine clinical practice
Davis AR, Stone SL, Oran AR, Sussman RT, Bhattacharyya S, Morrissette JJD, Bagg A. Targeted massively parallel sequencing of mature lymphoid neoplasms: assessment of empirical application and diagnostic utility in routine clinical practice. Mod Pathol. 2020 Dec 12. doi: 10.1038/s41379-020-00720-7. Online ahead of print.
Memory Sequencing Reveals Heritable Single-Cell Gene Expression Programs Associated with Distinct Cellular Behaviors
Shaffer SM, Emert BL, Reyes Hueros RA, Cote C, Harmange G, Schaff DL, Sizemore AE, Gupte R, Torre E, Singh A, Bassett DS, Raj A. Memory Sequencing Reveals Heritable Single-Cell Gene Expression Programs Associated with Distinct Cellular Behaviors. Cell. 2020 Aug 20;182(4):947-959.e17. doi: 10.1016/j.cell.2020.07.003. Epub 2020 Jul 30.
Haldar Lab
Mononuclear phagocyte system (MPS) with an emphasis on their role in the tumor microenvironment
Principal Investigator: Malay Haldar, MD, PhD
Perelman School of Medicine at the University of Pennsylvania
Real-world integration of genomic data into the electronic health record: the PennChart Genomics Initiative
Kelsey S Lau-Min, Stephanie Byers Asher, Jessica Chen, Susan M Domchek, Michael Feldman, Steven Joffe, Jeffrey Landgraf, Virginia Speare, Lisa A Varughese, Sony Tuteja, Christine VanZandbergen, Marylyn D Ritchie, Katherine L Nathanson. Genet Med. 2020 Dec 10. doi: 10.1038/s41436-020-01056-y. Online ahead of print.
An integrated multi-omics approach identifies epigenetic alterations associated with Alzheimer’s disease
TooManyCells identifies and visualizes relationships of single-cell clades
Schwartz GW, Zhou Y, Petrovic J, Fasolino M, Xu L, Shaffer SM, Pear WS, Vahedi G, Faryabi RB. Nat Methods. 2020 Apr;17(4):405-413. doi: 10.1038/s41592-020-0748-5. Epub 2020 Mar 2.
John W. Eckman Professor of Medical Science
Professor of Microbiology
Professor of Microbiology in Biochemistry and Biophysics
Scientific Director, High-Throughput Screening Core
Director, Program for Chemogenomic Discovery
Perelman School of Medicine at the University of Pennsylvania
Wang (Ping) Lab
The research focus of the Ping Wang lab is to use unmet clinical needs to inform the development of next generation diagnostics, and also to translate technologies developed in research into clinical practice. The goal is to enhance the ability to diagnose, prognose and monitor diseases earlier, more rapidly and more accurately. The Wang Lab collaborates widely with clinicians, engineers and industry.Prinicipal Investigator: Ping Wang, PhD
