Content tagged "Bioinformatics":

Herman Lab

Development of computational strategies, methods, and models for improving screening for underdiagnosed diseases, including primary aldosteronism
Principal Investigator: Daniel S. Herman, PhD

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Neoantigen Dissimilarity to the Self-Proteome Predicts Immunogenicity and Response to Immune Checkpoint Blockade

Richman LP, Vonderheide RH, Rech AJ. Cell Syst. 2019 Oct 8. pii: S2405-4712(19)30307-2. doi: 10.1016/j.cels.2019.08.009. [Epub ahead of print]

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Quantitation of Femtomolar‐Level Protein Biomarkers Using a Simple Microbubbling Digital Assay and Bright‐Field Smartphone Imaging

Chen H, Li Z, Zhang L, Sawaya P, Shi J, Wang P. Angew Chem Int Ed Engl. 2019 Jul 25. doi: 10.1002/anie.201906856. [Epub ahead of print]

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Whole Slide Imaging Versus Microscopy for Primary Diagnosis in Surgical Pathology: A Multicenter Blinded Randomized Noninferiority Study of 1992 Cases

Mukhopadhyay S, Feldman MD, Abels E, Ashfaq R, Beltaifa S, Cacciabeve NG, Cathro HP, Cheng L, Cooper K, Dickey GE, Gill RM, Heaton RP Jr, Kerstens R, Lindberg GM, Malhotra RK, Mandell JW, Manlucu ED, Mills AM, Mills SE, Moskaluk CA, Nelis M, Patil DT, Przybycin CG, Reynolds JP, Rubin BP, Saboorian MH, Salicru M, Samols MA, Sturgis CD, Turner KO, Wick MR, Yoon JY, Zhao P, Taylor CR. Am J Surg Pathol. 2017 Sep 28. doi: 10.1097/PAS.0000000000000948. [Epub ahead of print]

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Jacquelyn Roth, PhD, DABMGG

Associate Professor of Clinical Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania

Associate Vice Chair for Quality and Patient Safety
Director of Quality and Compliance, Division of Precision and Computational Diagnostics

Yuk Yee Leung, PhD

Research Assistant Professor of Pathology and Laboratory Medicine
University of Pennsylvania Perelman School of Medicine

Accurate and reproducible invasive breast cancer detection in whole-slide images: A Deep Learning approach for quantifying tumor extent

Cruz-Roa A, Gilmore H, Basavanhally A, Feldman M, Ganesan S, Shih NNC, Tomaszewski J, González FA, Madabhushi A. Sci Rep. 2017 Apr 18;7:46450. doi: 10.1038/srep46450.

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Standards and Guidelines for the Interpretation and Reporting of Sequence Variants in Cancer

Li MM, Datto M, Duncavage EJ, Kulkarni S, Lindeman NI, Roy S, Tsimberidou AM, Vnencak-Jones CL, Wolff DJ, Younes A1, Nikiforova MN. A Joint Consensus Recommendation of the Association for Molecular Pathology, American Society of Clinical Oncology, and College of American Pathologists. J Mol Diagn. 2017 Jan;19(1):4-23. doi: 10.1016/j.jmoldx.2016.10.002.

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Next Generation Sequencing for the Detection of Actionable Mutations in Solid and Liquid Tumors

Fox AJ, Hiemenz MC, Lieberman DB, Sukhadia S, Li B, Grubb J, Candrea P, Ganapathy K, Zhao J, Roth D, Alley E, Loren A, Morrissette JJ. J Vis Exp. 2016 Sep 20;(115). doi: 10.3791/52758.

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Daniel S. Herman, MD, PhD

Assistant Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
Perelman School of Medicine at the University of Pennsylvania 
Director, Endocrine Laboratory

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