Perelman School of Medicine at the University of Pennsylvania
Complement modulates the cutaneous microbiome and inflammatory milieu
Chehoud C, Rafail S, Tyldsley AS, Seykora JT, Lambris JD, Grice EA.
Proc Natl Acad Sci U S A. 2013 Sep 10;110(37):15061-6. doi: 10.1073/pnas.1307855110. Epub 2013 Aug 26.
PMID: 23980152 | PMCID: PMC3773768
T cell development requires constraint of the myeloid regulator C/EBP-α by the Notch target and transcriptional repressor Hes1
De Obaldia ME, Bell JJ, Wang X, Harly C, Yashiro-Ohtani Y, DeLong JH, Zlotoff DA, Sultana DA, Pear WS, Bhandoola A.
PMID: 24185616 | PMCID: PMC4038953
Nat Immunol. 2013 Dec;14(12):1277-84. doi: 10.1038/ni.2760. Epub 2013 Nov 3.
Peptide inhibitors of C3 activation as a novel strategy of complement inhibition for the treatment of paroxysmal nocturnal hemoglobinuria
Risitano AM, Ricklin D, Huang Y, Reis ES, Chen H, Ricci P, Lin Z, Pascariello C, Raia M, Sica M, Del Vecchio L, Pane F, Lupu F, Notaro R, Resuello RR, DeAngelis RA, Lambris JD.
Blood. 2014 Mar 27;123(13):2094-101. | doi: 10.1182/blood-2013-11-536573. Epub 2014 Feb 4.
PMID: 24497537 | PMCID: PMC3968392 [Available on 2015/3/27]
Perelman School of Medicine at the University of Pennsylvania
Cancro Lab
The Cancro laboratory is currently pursuing studies focused on mechanisms of B cell homeostasis and how these impact autoimmunity and aging. These have led to the characterization of a novel receptor for BLyS, a TNF family member that controls B cell numbers and determines the stringency of B cell selection.
Principal Investigator: Michael Cancro, PhD
Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Vice Chair for Faculty Development and Academic Affairs
Department of Pathology and Laboratory Medicine
Emeritus Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
