Diacylglycerol kinase ζ promotes allergic airway inflammation and airway hyperresponsiveness through distinct mechanisms
Singh BK, Lu W, Schmidt Paustian AM, Ge MQ, Koziol-White CJ, Flayer CH, Killingbeck SS, Wang N, Dong X, Riese MJ, Deshpande DA, Panettieri RA Jr, Haczku A, Kambayashi T. Sci Signal. 2019 Sep 3;12(597). pii: eaax3332. doi: 10.1126/scisignal.aax3332.
Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade
Benci JL, Johnson LR, Choa R, Xu Y, Qiu J, Zhou Z, Xu B, Ye D, Nathanson KL, June CH, Wherry EJ, Zhang NR, Ishwaran H, Hellmann MD, Wolchok JD, Kambayashi T, Minn AJ. Cell. 2019 Aug 8;178(4):933-948.e14. doi: 10.1016/j.cell.2019.07.019.
TOX transcriptionally and epigenetically programs CD8+ T cell exhaustion
Khan O, Giles JR, McDonald S, Manne S, Ngiow SF, Patel KP, Werner MT, Huang AC, Alexander KA, Wu JE, Attanasio J, Yan P, George SM, Bengsch B, Staupe RP, Donahue G, Xu W, Amaravadi RK, Xu X, Karakousis GC, Mitchell TC, Schuchter LM, Kaye J, Berger SL, Wherry EJ. Nature. 2019 Jun 17. doi: 10.1038/s41586-019-1325-x. [Epub ahead of print]
Genetic meta-analysis of diagnosed Alzheimer’s disease identifies new risk loci and implicates Aβ, tau, immunity and lipid processing
Kunkle BW, Benjamin Grenier-Boley B, […] Trojanowski JQ, Van Deerlin VM, […] Wang LS, Schellenberg GD, Lambert JC, Pericak-Vance MA. Nat Genet. 2019 Mar;51(3):414-430. doi: 10.1038/s41588-019-0358-2. [Epub 2019 Feb 28]
Longitudinal HIV sequencing reveals reservoir expression leading to decay which is obscured by clonal expansion
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Assistant Professor of Pathology and Laboratory Medicine
Assistant Professor of Microbiology
Perelman School of Medicine at the University of Pennsylvania
Assistant Professor of Pathology and Laboratory Medicine
Assistant Professor of Microbiology
Perelman School of Medicine at the University of Pennsylvania
Lineage-Determining Transcription Factor TCF-1 Initiates the Epigenetic Identity of T Cells
Johnson JL, Georgakilas G, Petrovic J, Kurachi M, Cai S, Harly C, Pear WS, Bhandoola A, Wherry EJ, Vahedi G. Immunity. 2018 Feb 20;48(2):243-257.e10. doi: 10.1016/j.immuni.2018.01.012.
Commensal Microbes Induce Serum IgA Responses that Protect against Polymicrobial Sepsis
Wilmore JR, Gaudette BT, Gomez Atria D, Hashemi T, Jones DD, Gardner CA, Cole SD, Misic AM, Beiting DP, Allman D. Cell Host Microbe. 2018 Feb 7. pii: S1931-3128(18)30040-4. doi: 10.1016/j.chom.2018.01.005. [Epub ahead of print]
An Atlas of B-cell Clonal Distribution in the Human Body
Meng W, Zhang B, Schwartz GW, Rosenfeld AM, Ren D, Thome JJC, Carpenter DJ, Matsuoka N, Lerner H, Friedman AL, Granot T, Farber DL, Shlomchik MJ, Hershberg U, Luning Prak ET. Nat Biotechnol. 2017 Aug 21. doi: 10.1038/nbt.3942. [Epub ahead of print]
