Therapeutic C3 inhibitor Cp40 abrogates complement activation induced by modern hemodialysis filters
Reis ES, DeAngelis RA, Chen H, Resuello RRG, Ricklin D, Lambris JD. Therapeutic C3 inhibitor Cp40 abrogates complement activation induced by modern hemodialysis filters. Immunobiology. 2014 Nov 3. [Epub ahead of print] | doi: 10.1016/j.imbio.2014.10.026
Perelman School of Medicine at the University of Pennsylvania
Doms Lab
Research in the Doms lab utilizes a wide array of cell biological, biochemical, genetic, and immunological techniques to study membrane proteins important in HIV/AIDS pathogenesis as well as relatively new research projects on Rift Valley Fever virus and other members of the bunyavirus family in which we seek to identify host cell pathways that are used by these viruses to infect cells.
Principal Investigator: Robert W. Doms, MD, PhD
Bassing Lab
DNA repair, genomic instability, cancer, lymphocyte development, V(D)J recombination, class switch recombination, auto-immunity
Principal Investigator: Craig H. Bassing, PhD
Weitzman Lab
Virology, Virus Replication, DNA Damage and Repair, Genome Instability, Viral Vectors
Principal Investigator: Matthew D. Weitzman, PhD
Spinner Lab
Human Genetics, Notch signaling in human disease, Alagille syndrome, Biliary Atresia, SNP array analysis, copy number variation, human disease gene identification by mapping deletions, Ring Chromosome 14, Ring Chromosome 20, Genome wide association studies, next-generation sequencing, chromosomal analysis
Principal Investigator: Nancy B. Spinner, PhD
Marks Lab
Regulation and diseases of intracellular protein transport and organelle biogenesis; Regulation of the formation of functional amyloid in organelle biogenesis; Regulation of antigen processing and toll-like receptor signaling by endosomal trafficking pathways.
Principal Investigator: Michael S. Marks, PhD
Burkhardt Lab
Regulation of cytoskeletal dynamics in T cells and dendritic cells, and cytoskeletal control of the immune response
Principal Investigator: Janis K. Burkhardt, PhD
Argon Lab
Functions of molecular chaperones in modulating cell surface receptors and secreted proteins
Principal Investigator: Yair Argon, PhD
