Research Associate Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Contact Information
Hospital of the University of Pennsylvania
1 Maloney Building
3400 Spruce Street
Philadelphia, PA 19104
Office: 215-615-3202
Fax: 215-615-3206
Email: kelvincl@pennmedicine.upenn.edu
Research Expertise
My research aims to improve our understanding of the synucleinopathies, a group of neurodegenerative disorders that include Parkinson’s disease (PD), Lewy body dementia and multiple system atrophy (MSA).
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The John H. Ware 3rd Endowed Professor in Alzheimer's Research
Perelman School of Medicine at the University of Pennsylvania
Co-Founder, Center for Neurodegenerative Disease Research
Co-Director, Marian S. Ware Center for Alzheimer's Drug Discovery Program
Contact Information
Center for Neurodegenerative Disease Research
3rd Floor, Maloney Building
3600 Spruce Street
Philadelphia, PA 19104-4283
Office: (215) 662-6427
Fax: (215) 349-5909
Email: VMYLEE@UPENN.EDU
Research Expertise
Research Interests
Biology of tau, synucleins, TDP-43 and amyloid beta precursor proteins (APPs) in health and disease.
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Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Director, Center for Neurodegenerative Disease Research
Co-Director, Institute of Aging
Contact Information
Perelman School of Medicine at the University of Pennsylvania
Department of Pathology and Laboratory Medicine
Stellar-Chance Laboratories, Room 613A
422 Curie Blvd
Philadelphia, PA 19104
Tel: 215-898-0908
Email: edward.lee@pennmedicine.upenn.edu
Research Expertise
Alzheimer's disease
Frontotemporal lobar degeneration
Amyotrophic lateral sclerosis
Clinical Expertise
Neuropathology
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Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Contact Information
Department of Pathology and Laboratory Medicine
Stellar Chance, 405A
422 Curie Blvd.
University of Pennsylvania
Philadelphia, PA 19104-6100
Office: 215-573-5037
Fax: 215-573-6317
Email: johnsonb@pennmedicine.upenn.edu
Research Expertise
Research Interests
Molecular biology of aging, cell senescence, Werner syndrome, telomeres,
recombination, G-quadruplexes, neurodegeneration, transplantation.
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Emeritus Professor of Pathology and Laboratory Medicine at the Children's Hospital of Philadelphia
Perelman School of Medicine at the University of Pennsylvania
Contact Information
Children's Hospital of Philadelphia
Department of Pathology and Laboratory Medicine
S 34th St & Civic Center Blvd
Main Building, Suite 5NW15
Philadelphia, PA 19104
Office: 267-426-5504
Fax: 267-426-7783
Itmat Expertise
Developmental neuropathology
Malformations and peditatric degenerative disorders of the nervous sytem
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Research Professor of Pathology and Laboratory Medicine
Perelman School of Medicine at the University of Pennsylvania
Director of Drug Discovery
Center for Neurodegenerative Disease Research
Contact Information
Center for Neurodegenerative Disease Research
Perelman School of Medicine at the University of Pennsylvania
Maloney Building, 3rd Floor
3600 Spruce Street
Philadelphia, PA 19104
Tel: 215-615-5262
Email: kbrunden@upenn.edu
Drug discovery and development, neurobiology, biochemistry and pharmacology
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Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, et al.
Nat Genet. 2013 Dec;45(12):1452-8. doi: 10.1038/ng.2802. Epub 2013 Oct 27.
PMID: 24162737 | PMCID: PMC3896259
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Lee (Edward) Lab
The Translational Neuropathology Research Laboratory, with Principal Investigator Dr. Edward Lee, aims to understand the root causes of human neurodegenerative diseases to translate into specific disease-modifying therapies. The lab uses an interdisciplinary approach to address the mechanisms of neurodegeneration, using and developing such cutting-edge techniques as high-resolution, multi-spectral, 3-dimensional confocal imaging and next-generation sequencing.
Edward Lee, MD, PhD, Profile
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Professor of Pathology and Laboratory Medicine at the
Hospital of the University of Pennsylvania
Perelman School of Medicine at the University of Pennsylvania
Contact Information
Hospital of the University of Pennsylvania
Department of Pathology and Laboratory Medicine
7.103 Founders Pavilion
3400 Spruce Street
Philadelphia, PA, 19104
Tel: 215-662-6644
Fax: 215-662-7529
Email: vivianna.vandeerlin@pennmedicine.upenn.edu
Research Expertise
My research interests are focused in the genetics of neurodegenerative diseases, in particular frontotemporal lobar degeneration (FTLD), amyotrophic lateral sclerosis (ALS), Parkinson's disease (PD), and Alzheimer's disease (AD).
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Assistant Professor of Pathology and Laboratory Medicine at the Hospital of the University of Pennsylvania
Perelman School of Medicine at the University of Pennsylvania
Associate Vice Chair for Translational and Clinical Research
Department of Pathology and Laboratory Medicine
Contact Information
Hospital of the University of Pennsylvania
Department of Pathology and Laboratory Medicine
6 Founders Pavilion
3400 Spruce Street
Philadelphia, PA 19104
Research Expertise
Brain development, mouse models, in utero electroporation in mouse models, molecular biology
Itmat Expertise
Brain tumors, neuropathology and genetic/molecular pathology advances
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